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Objective This phase I/II study sought to explore intrathecal administration of mesenchymal stem cells (MSCs) as therapeutic approach to multiple system atrophy (MSA) Methods Utilizing a doseescalation design, we delivered between 10 and 0 million adiposederived autologous MSCs intrathecally to patients with early MSA Patients were closely followed with clinical, laboratory,B#0 Q ^ <Is a American computeranimated mystery comedy film based on HannaBarbera's ScoobyDoo franchise, produced by the Warner Animation Group and distributed by Warner Bros PicturesThe film is directed by Tony Cervone from a screenplay by Adam Sztykiel, Jack Donaldson, Derek Elliott, and Matt Lieberman, and a story by Lieberman, Eyal Podell, and Jonathon E Stewart



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